300K–320K USD / year
CMC & Manufacturing Lead, Life Sciences
OtherHybrid — United States
Published on 2026-11-13
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About this role
Lead chemistry, manufacturing, and controls strategy for genetic medicines from early development through clinical supply. Partner with external manufacturers and Anthropic researchers to make CMC work more efficient and explore how AI can accelerate drug development.
About the company
Anthropic builds reliable and interpretable AI systems, including the Claude family of models, for businesses and developers. The company focuses on AI safety research and practical AI assistants for enterprise and consumer use.
The team
Life Sciences team
Stack
Lipid nanoparticles (LNP)mRNAGuide RNA (gRNA)Adeno-associated virus (AAV)Antisense oligonucleotides (ASO)Claude
What you'll do
- Guide CMC and manufacturing strategy from early development through clinical supply
- Oversee external process, analytical, formulation, fill-finish, stability, and release work
- Manage quality oversight for externally manufactured material, including audits and batch disposition
- Assess novel manufacturing, analytical, and delivery technologies
- Develop approaches to reduce the time and cost of producing clinical material while protecting quality and patient safety
- Work with researchers and engineers to identify and evaluate real-world CMC uses for Claude
- Identify CMC and supply-chain risks and communicate decisions and tradeoffs
What we're looking for
- Industry experience leading CMC for gene therapy, gene editing, or nucleic acid products from preclinical development into the clinic
- Deep expertise in several of LNP, mRNA, gRNA, AAV, and ASO manufacturing, characterization, and release
- Knowledge of GMP manufacturing and regulatory CMC requirements, including IND CMC sections
- Experience selecting and managing CDMOs, CROs, and other external partners, including technology transfer and quality oversight
- Track record of creative process, analytical, or supply solutions for novel products
- Ability to assess technologies using data and communicate recommendations clearly
- Curiosity about AI and alignment with Anthropic’s mission
Nice to have
- 10+ years in biotechnology or pharmaceutical CMC and gene therapy development
- Advanced degree in a relevant scientific or engineering field
- Experience with rare-disease or small-population programs, or platform-based manufacturing
- Experience leading discussions with FDA, EMA, or MHRA
- Hands-on GMP quality experience, including audits, quality agreements, deviation review, and batch disposition
- Experience building a CMC function or working in a fully outsourced model
- Experience with small-batch or rapid-turnaround GMP manufacturing and accelerated release testing
- Hands-on use of LLM tools such as Claude
Benefits
- Generous vacation and parental leave
- Flexible working hours
- Optional equity donation matching